English
Pronunciation
audio|MPTPpronounce.ogg|Audio (US)
initialism
MPTP
- 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Noun
en-noun|-
- neurotoxin A byproduct of synthetic heroin, or MPPP, which causes Parkinsonian symptoms in users.
- neurotoxin A neurotoxin which degrades into 1-methyl-4-phenylpyridinium| MPP+ after crossing the blood brain barrier, which causes a degredation of the dopaminergic neurons within the substantia nigra.
Quotations
2005 Dec 29 Petzinger, et al. Journal of Neuroscience Research 1
:The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MPTP provides an excellent opportunity to study repair and response to injury in the basal ganglia.
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