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Definitions mainframe noun  A large, powerful computer able to manage very many simultaneous tasks and communicate with very many connected terminals; used by large, complex organizations (such as banks and supermarkets) where continuously sustained operation is vital Supplemental Details:Sponsor an extended definition for mainframe for as little as $10 per month. Click here to contact us.        Find:   Words Starting With:   Words Ending With:   Words Containing:   Words That Match:    Translate Into:    Dutch   French   German    Italian   Spanish     Show 51015202550100250500 results per page. Browse the Dictionary A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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